There are some important aspects you should consider first.
Streaming
Let's imagine the 100 MB file is received by the service A which transfers it to service B, which, in turn, uses service C to do the actual parsing of the proprietary format.
The wrong approach would be for the services A and B to start sending the file to the underlying service only after they completely received the file from the client:

Instead, as soon as they start receiving the file, they should stream it to the underlying service.

This means that you're not waiting the time it takes to transfer 100 MB three times, but only one time, plus the latency...
Latency
Latency, on the other hand, cannot be avoided. Every intermediary service would still have to open the HTTP/HTTPS connection to the underlying service, before starting to transfer the file.
If your micro-services are located in the same data center, chances are the latency is a matter of a few milliseconds. If the services are hosted in different data centers, the latency may grow. With a high number of intermediaries, this can become a problem, and it will affect even small requests.
Possible DOS
When using the streaming technique, you should check that you don't open yourself to a possible DOS attack. The risk is that the intermediaries will keep the HTTP connection as long as the client is sending the file. The DOS attack would then consist of sending lots of files at a very low speed in order to exhaust the connections that the services are able to process.